The breakthrough offers hope to countless people who have become incontinent through damage to their own anal sphincters. The spare-part sphincters were made with some human cells, but have been implanted only in mice so far. Researchers made them by growing donated smooth muscle cells from human sphincters alongside gut nerve cells from mice in circular moulds. More importantly, it survived and grew when implanted beneath the skin in the upper back of mice.
Artificial anal sphincter could limit bowel incontinence
SURG Artificial Anal Sphincter for the Treatment of Severe Fecal Incontinence
In fecal incontinence FI , surgery may be carried out if conservative measures alone are not sufficient to control symptoms. There are many surgical options described for FI, and they can be considered in 4 general groups. The relative effectiveness of surgical options for treating fecal incontinence is not known. A surgical treatment algorithm has been proposed for FI,  although this did not appear to include some surgical options. Isolated sphincter defects may be initially treated with sphincteroplasty and if this fails, the patient can be assessed for sacral nerve stimulation. If this fails, neosphincter with either dynamic graciloplasty or artificial anal sphincter may be indicated. This operation aims to repair sphincter defects which may be of unknown cause or damage from trauma usually caused by obstetric damage.
Experience with a new prosthetic anal sphincter in three coloproctological centres
There is an internal and external sphincter surrounding the anus. As the urge to defecate increases, you can contract or squeeze your sphincters to gain more control. When you cannot control these sphincter muscles, bowel incontinence also called accidental bowel leakage or fecal incontinence may happen. Surgery to implant an artificial sphincter involves placing an inflatable sphincter around the anus. A pump placed inside the body in the labia or scrotum is used to deflate the device, allowing fecal matter to pass through at the appropriate time.
Fecal incontinence is a common and severely disabling disorder. For patients with severe fecal incontinence, surgery may prove to be the only adequate treatment option. This study reports on 43 patients that were treated with a prosthetic sphincter system between and in three coloproctological centres. Main Outcome Measures: complications, anal pressures before and after surgery, fecal continence score.